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ASO Designer

ASO Designer

ASO Designer leverages deep learning to optimize oligonucleotides by predicting their effects on exon inclusion, skipping, and mRNA degradation.

Input
History
About
User Guide
icon
Mechanism
Parameters
* Gene Name
* Transcript
* Target Exon
Valid range: 0–0, max interval length 500 bp
* ASO Length
Mutation (opt.)
Enter variants in HGVS format, e.g.
1. c.123T>A
2. c.123_124TG>C
3. c.169+2T>C
4. c.45_46insGC
5. c.36_38del
6. c.45_47delinsTT
7. c.-1G>T
8. c.*16G>T
9. c.23+4_23+5GG>CT
10. p.Ser3435Ter
Exon
Intron
Results
Evaluation indicators
emptyPlease click the ‘Design’ button to start ASO sequence discovery
Target Region
emptyPlease click the ‘Design’ button to start ASO sequence discovery
History Record
Update Time
Status
Updater
Review
No data available
0 Results, 10 per Page
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About
Antisense oligonucleotides (ASOs) Designer is a predictive tool for antisense therapy development. By simulating exon inclusion, skipping, and mRNA degradation, it identifies optimal target regions and generates efficacy scores to prioritize high-potency candidates.